In the 1985 NFL Draft, Fralic was selected by the Atlanta Falcons with the second overall pick. He became a starter for the Falcons at offensive guard during his rookie season. He went on to be named All-Pro in 1986 & 1987, and was named to the Pro Bowl from 1986 to 1989. During this time, the 6 ft 5 in (1.96 m), 280 lb (127 kg) Fralic developed a reputation as a ferocious run blocker.
At the end of his NFL career, he was one of the first players to take advantage of the new free agent system and jumped from the Atlanta Falcons to the Detroit Lions, almost doubling his pay to $1.6 million for the 1993 season.